Regenerative Biomaterials

Driven by curiosity, challenged by translation

The Regenerative Biomaterials research group at Radboudumc creates novel biomaterial-based therapies for regeneration of hard tissues. Overall, our main aim is to decipher which physicochemical properties of biomaterials are able to trigger the natural self-healing capacity of hard tissues. Our design philosophy is highly translational and aimed at bridging the gap between basic and clinical sciences. To this end, experimental data are translated to pre-clinical and clinical studies to benefit patients.

We strive to overcome major shortcomings of conventional biomaterials by smart design of biomaterials with improved biological, mechanical and handling performance. To this end, we synthesize a wide range of nano- and microstructured biomaterials including injectable and biodegradable hydrogels and cements, colloidal and self-healing composites, barrier membranes and coatings, as well as organic or inorganic nanoparticles. These biomaterials are functionalized with various types of therapeutics and/or patient-derived cells to tune their capacity to induce tissue regeneration for both healthy and diseased patients.

Dental Research Laboratory

- cutting edge facilities for advanced research - 

The Regenerative Biomaterials group coordinates the organization of the shared Dental Research Laboratory, which is housed at the Department of Dentistry at Radboudumc. The Dental Research Laboratory is a state-of-the-art 680 sqm
facility for basic and translational research on oral biology, restorativedentistry and biomaterials research. This laboratory provides access to a wide range of modern facilities to facilitate translation of (pre)clinical biomaterials research to novel therapies and medical devices. The Dental Research Laboratory is professionally managed by a group of academic staff members and six experienced lab technicians.